Have you gone to the Asus site and do they have Win10 drivers yet? Windows 10 came out with a lot of devices with no supported drivers; I have to use a third-party driver to get sound from my brilliant Asus sound card.
I just poked over to Asus support and there is a Win10-specific driver for the touchpad. You might want to try that: https
/www.asus.com/Commercial-Notebooks/ASUS_Transformer_Book_Flip_TP300LA/HelpDesk_Download/ , and any other Win10 specific drivers for that model.