Chrome launch fast, opens pages fast enough also, and can handle good usage. What I don't like about Chrome is lack of customization options. That's a good thing for those people who otherwise would have 7-8 toolbars in their browser and no idea how they got there. I have Chrome and use it from time to time for a quick browsing.
Opera has all the customization options I like, launches slow, but opens pages really fast and with really small CPU usage. But handles scripts and even page appearance in an unsatisfactory manner. I have Opera, and use it often for Tom's Hardware, especially when getting multiple tabs, but rarely for anything else.
Internet Explorer hangs at version 6 for the fun of browsing through Windows Explorer, and extreme rare cases of compatibility.
Firefox rests as my main browser, but only because I am unsatisfied with Opera compatibility and Chrome lack of customizations.