I had the same problem for a few months now of video stuttering only in chrome, especially on facebook, and disabling hardware acceleration in the chorme advanced settings worked great and fixed the problem! Thank you!
I did both of the suggestions provided - cleared the contents of C:\Windows\SysWOW64\Macromed\Flash (I'm on Windows 7 64-bit) (yes, one file wouldn't delete)... plus I disabled Hardware Acceleration in the Advanced Settings for Chrome... and...
I've been having the stuttering problem described in this thread for the last few months and went through the exercise of changing out a high-end AMD card for an Nvidia card. That didn't help at all. So I wiped the machine and reinstalled Windows. That didn't help either. Very happy that I came across this thread. Disabling hardware acceleration in Adobe Flash completely resolved the problem.
I have a Dell XPS 8500 and a Dell XPS 8700 running Windows 8.1 and both have intermittent "stuttering" problems playing back videos (youtube, ect...). After much searching I found that the most likely cause is CPU DPC Latency, which in my Dells is apparently caused by the Wireless LAN adapter. I went to device manager and disabled the Wireless LAN adapter (I have a wired home LAN) and the problem seems to have disappeared (while I was at it I disabled the Bluetooth adapter also, don't have need for either). If you are using a Wireless LAN I'm not sure what the fix is (maybe disabling the LAN port )