I've worked in a plastic company... Titanium Dioxide is considered "Potentially Cancerous" in powder form! We had to wear dust masks working with this material, and even then, they had to remove this material from the ingredient list of plastic in 2008!
Don't believe Asian safety rules! The European ISO2008 norm gets only stricter and stricter...
There's a bit of common sense a person has, to know that ANY contact with ANY chemical, is ALWAYS disadvantageous!
A human body is created to interact with bio materials, not chemicals.