Machine infected with a mailbot can't detect

[techguy911]

I have a computer here at work seems its infected by some sort of mail bot mailing out adverts to Viagra i noticed this when it mail itself a copy to our mailbox.

I have tried just about every major av and anti-spyware out there 30 in all and nothing can be found?.

anyone know of any specialized software to do this?.

I tried looking for hidden processes using a few apps but i don't see anything hiding ie. prob a new rootkit+worm.

 

[PFZ1]

Well i`ve just had 48hrs of fun hunting down the cause of pop up adverts, ran NORTON`s (Pile of KAK) oh cause after making sure updated!! Found sod all thought to my self stuff that uninstalled and installed mcafee(another Pile of KAK but not as bad as norton`s) And it went balistic 60+infections found ok killed them still getting pop-ups ---..... WTF!!!! uninstalled mcafee installed trend micro 10more infections found OK TIME FOR OVERKILL...... TIME TO KICK VIRUS ARSE AND CHEWBUBBLE GUM.... installed three different BOT&SPYWARE killers 50 more infected files later DAH DAH Its fixed and PUKA

 

[techguy911]

I have tried all of those i can see traffic from that machine with no apps running the network is always busy sending out emails even though no mail program is open.

Need something to watch and close ports...