I tell you, a question like this could gather a whole seething debate, Here are the issues from real world experience. Adware will sneak in because someone was not quite paying attention as when something was downloaded or links clicked when in a site eyc.. (a few others ways of course). When this happens you have now bypassed all security. The virus/malware protection usually see's this as a regular program and, is of no more use then using malwarebytes to remove microsoft office. All of this is opinion when it comes to security programs. All seem to have the ol' pro's and cons. I do not dance around issues here thinking someone might disagree, I use kaspersky with malwarebytes. I have not had an issue in over three years. Not a single one.