Run your fsb and memory interface in synch in each case ! If you have a 100 Mhz fsb, you will get much better results running it 133, even if you have to decrease your mulitplier. Aces did a nice review on this, when he tested the KT133A (I presume you have a board based on this chipset).
As for going beyond 133.. personally I prefer to run my PCI, AGP and memory at standard speeds.. makes trouble shooting that much easier. For me, its simply not worth the little bit of extra speed. But, if you it doesn’t scare you, the higher the fsb, the better the performance (although beyond 133 you’re likely only to see improvements in benchmarks, like Sandra, but not any realworld performance to speak of)