Softmodding is slightly dangerous for the console. Also, the WODE is indistinguishable from the Wii's DVD drive to Nintendo, so when you update your console's firmware the WODE still works, unlike softmods. Also, the WODE itself does not allow homebrew to run without first softmodding the console, the title of the article is wrong.
The main reason I bought a WODE is to have all my games in one place without having the kids shuffling around the discs without requiring any softmods. It also works with any version of the Wii firmware not only 4.1 and lower although any version newer than 4.1 does not allow the running of out of region games.
You should check out the WODE's main site at www.wodejukebox.com they do a much better job at explaining the WODE than the few misleading articles that have been floating around for the last few days.
The WODE team has also mentioned that they are working on a similar product for the Xbox 360.
My last defence of the WODE is that the above mentioned Softmod USB Loaders require that your external harddrive be formatted in the WBFS file system and that games be transfered to the drive using special software. The WODE allows your disc images to reside on any popular filesystem in ISO or the smaller WBFS file format. It also runs and rips Gamecube game which I beleive the USB loaders can't run.