Hey darkchief,
Yes, you can clone the original drive onto the ssd while it is connected via the optical drive's msata port. If the ultimate goal is to have the ssd be the boot drive for the computer you should know up front that, if you do this you're going to need to change your boot options in system preferences by selecting the ssd as the drive you'd like to boot from or you won't reach the boot times you would otherwise. Hope you're having a good day.