I have problem on backing up on my server for 2days now,even to backup on the external i get the same error:CANNOT CREATe OR REPLACE S-5-3-42-2819952290-8240758988-879315005-3663: ACCESS DENIED.
Make sure the disk is not full or write-protected and that the file is not currently in use.
Is the issue that it skips over that file, or that the backup fails when it hits tha file/folder? That folder name sounds like one of the temp names that gets created when a patch or service pack is installed, most likely it's not an issue to not back it up.
If your backup fails due to this, what backup software are you using? You may either need to use a better software that won't hang on files it can't back up, or just exclude that file/folder from the backup.