This looks like an
X-Y problem. You probably
don't want make Skype act like a 64-bit application. What you really want is to resolve:
Socloseagain :
...the same error as the non-patches version...
Having been a long time user of Skype 4.2 until recently and knowing about the recent deprecation of old versions, and taking into consideration your later posts, I'm going to make an educated guess that your problem is the version check that is preventing you from logging in (and probably giving a misleading error if it's anything like 4.2). Of course I'm still guessing, since you haven't given us the error.
Socloseagain :
And @ex_bubblehead 3.8 is supported ( patched )...
No, 3.8 is not supported. Only Skype 6.14 and later are supported. There's a difference between working software and supported software. Windows XP works but is not supported (unless you have commercial arrangements).
Do you have links to this "patch"? Without knowing exactly what hacks you're trying to apply it's impossible to know if it's even physically possible to do what you want. Note that depending on the source and nature of this patch the link may be promptly removed. It may be better to just PM me the link.