Hello... 3) well if it's USB3 ports only... you need a pre-install an USB3.0 driver and add it to the USB files.
4) if it's a legacy, non uefi BIO's, then you need to format the USB2 stick to FAT32 and click "make Bootable" in your ISO transfer program.
The first thing you should try doing is making a bootable USB2 stick first... if you have another computer, insert the USB2 stick and right click it-format-FAT32-click box "create MS-DOS start up disk" and see if that will boot from your USB2 port on your lappy as a TEST. B /
If you can make a working "bootable" USB stick then you just need to tranfer the WIN10 ISO to the stick after that, with those settings.