I very nearly went for the Pixel 6 Pro but decided to wait for the S22. My preference would be the rumoured S22 Pro which is top spec but a smaller size than the Ultra. That appeals to me, I don't like phones at the Ultra size.
On the camera side, I would say that computational is just one aspect of photography, and while the Pixel photographs are technically impressive, they look quite artificial to my eyes. I couldn't really explain it but MKBHD discusses it and he thinks it is the HDR processing being too strong. With a Pixel camera it would be hard to photograph a silhouette against the sun - the Pixel would show the detail of the object instead of just the black outline as intended.. Samsung and Apple cameras take photos that look more realistic then the Pixel 6 does at the moment. Samsung also has a Pro mode where you can control shutter speed and even metering. Pixel phones don't have this.
There are also a few reviews pointing out issues with the Pixel 6 battery life. This may well be software issues that get patched soon, but again, I'd rather wait for the S22 to launch then decide.