Will stand on the matching of hardware and software.
Be sure that the gtrx 1080 ti is enough "power" to meet the software's minimal requirements at least. Overall, minimal is not likely to work all that well so you need to read the software's requirements and meet or exceed the recommended hardware specifications.
Minimal may work but be so slow that the end productivity is negligible.
And, has been asked, do you really plan to have twelve? May lead to other problems and concerns - you truly need to identify the requirements and any constraints (e.g., budget, power, cooling) imposed.