I wouldn't recommend it. 2 active anti-virus programs will often clash, and if they both scan the same file, each might detect a virus or an issue without there actually being one. And in general, a lot of weird things are gonna happen (Not counting significant system slow-down). If you want to run full protection, I would recommend anti-virus and anti-malware of your choice, any major or popular distributors of each should work well together. Additionally, as far as I can tell, Kaspersky has everything in it, including anti-malware, so you should probably just go with that and not worry about it that much.