Not necessarily driving them, they're old dell computer speakers and I just use a fiio 17 as my main sound card since my integrated one isn't working. The kind of cable I am using is the issue. Works fine when using a 6 inch cable.
the best way to do it would be to have a long usb cable so your keeping the connection digital for as long as possible and then have the dac closer to the speakers.
you could use an ethernet usb range extender and use cat 5 cable between.
Getting this http/www.newegg.com/Product/Product.aspx?Item=N82E16812119252. I realized I have another usb dac I could use dedicated for those speakers which will be nice. Then I could still have sound on my PC when those speakers are going.
no worries bud, just remember dont have the output on the dac maxed, have atleast half volume and use the amp in the speakers, will sound better that way with less pre amping.