Hi there, this doesn't sound like it would be related to Avast in any way, unless for some reason Chrome was compromised and it's being blocked. I'd check your virus chest as well as your exclusions and make sure that Chrome isn't being blocked.
However, since you're still seeing the problem with Avast disabled, my feeling is that you're OK on the above

I'd try uninstalling and reinstalling Chrome as well as making sure Windows is completely up to date as a start. You should also perform a full malware scan on your machine.