Terrific article, thanks, and actually the principles apply perfectly well to desktop as well as laptops. The key difference is that for a given state of technology, laptops have MUCH slower hard drives, somewhat slower CPUs, and most often absolutely anemic video subsystems. So when optimizing a laptop, the most noticable improvements will come from improvements to disk I/O and video.
While the price of Sysinternals' Contig and PageDefrag can't possibly be beat, I've found that the way programs like Diskeeper can reorganize your files and defrag the MFT is also vastly beneficial. Plus, once you install it and spend five minutes setting it up, you can forget about it completely. I use this software on every server, workstation and laptop I have and my employer - a fortune 500 company - specifies it in their standard server builds.
Also, since slower disk I/O is such a problem (and upgrading to faster drives is costly as well as difficult or sometimes not possible due to engineering obstacles related to the extra power and heat), it's good to keep in mind that disk transfer rates decrease to half the speed at the outer zones of the disk, and that the fuller the disk is, the longer most random access times will be. So a thorough cleanup of the files on the hard drive is a great idea, hopefully to leave 50% of the space free, or more. And the free space allows disk optimizers to work better.
Neosoul mentions performance improvements from memory upgrades. Indeed! Especially because paging is so awfully slow with laptop hard drives.
Sysinternals has a program called Process Explorer which can help better identify processes and their owners. It can take the mystery out of all those SVCHOST entries, for example.
The tip about organizing files is excellent and the recommendation to use folders sports an additional GUI performance benefit due to the way Windows' GUI manages icons and links. Likewise, mikefxu's idea to turn off Windows' eye candy speeds up the GUI and reduces the memory footprint.
The article states that "stopping Word will force you to edit messages using Outlook's much less user friendly text editor." Actually Outlook's native editor is more the sufficient for most people and turning off the option to use Word represents a huge performance improvement right there.
Keep up the good work!
-Brad