When I served as a Wizop for Compuserve back in the day, before we could release any uploaded file to on-line libraries, all files had to be scanned with two (2) AV programs. SOP was to have one always active. The file was downloaded to a temp folder and manually scanned with 1st one and then the 2nd AV program. No harm in using any number that you choose as long as only one is designated to "actively" scan files as they are opened.
Another common technique used on networked data drives is to have the server run its scheduled scan at say midnight and then have a networked box scan the data dive remotely at 3 am.
We used BD for quite sometime until management of the site license became too labor intensive. Upon renewal each year, Id download once and then sit down at each box to install from network drive or USB if a remote site. About 2 years ago, they switched do that i had to download it directly to each box.... was too time consuming so switched to Kaspersky.
6 products scored 100% detection in latest test ...
4 scored 5.0 / 5.0 / 5.0 ratings (Avira, Kaspersky, Norton, Trend Micro). Avira and Kaspersky did it 3 times in a row on Win 10. Kaspersky did it 3 times in a row on Win 10 and Win 7.
https

/www.av-test.org/en/antivirus/home-windows/