The 2 12 woofers/1100 watt mono amp will be your mono subwoofer. Should connect to a sub out of the headunit or mono sub out of an electronic crossover.
The 2 6.5 will be your stereo woofers in the doors. These would be connected to a passive crossover and the tweeters. Both the 2 6,5 and 2 tweeters would be driven by a 2 channel amp. Add the power ratings of the woofers and tweeters to get some idea of the max power that amp should have, This amp connects to the high pass out of the electronic crossover or the main output of the headunit.