Question regarding Rufus usb tool

Kurokidan

Estimable
Apr 27, 2014
2
0
4,510
Greetings,

I'm trying to make a new usb bootable version of Windows 10 Pro x64 and I can't decide which option to select regarding the partition scheme and file system. My system is quite new (4770k, z87 mobo with uefi). Should I go with typical option MBR and NTFS or is it better to go with GPT and FAT32? In the second option can I use NTFS with GPT?
 

Kurokidan

Estimable
Apr 27, 2014
2
0
4,510
Yes I am aware of the procedure but I just wanted to know mostly if it is possible to use NTFS instead of fat32 with GPT. Didn't fat32 had restrictions regarding file size ? Can it now support files larger than 4gb cause I knew it couldn't that's why we all turned to NTFS.